Hair loss can have various causes, including both normal hair shedding (which is typical, as people normally shed 50–100 strands of hair daily) and abnormal hair loss due to numerous factors. One of these factors is an abnormal waste removal system within the hair follicle cells, known as autophagy.
What is autophagy? How is it related to hair loss?
Autophagy It is the process of eliminating waste within cells, functioning to break down or remove damaged or unnecessary components, such as abnormal proteins and organelles known as degenerated ones, in order to maintain balance and generate energy within the cell (ATP) for efficient operation.
When autophagy in hair follicle cells malfunctions, it can lead to hair loss and thinning. This dysfunction can be categorized into two main types.
- Excessive Autophagy (Hyperactive Autophagy) It will cause hair follicle cells to break down more rapidly. When hair follicle cells break down quickly, the hair on the scalp is forced to enter the resting or shedding phase (Telogen Phase) more rapidly. In other words, excessive Autophagy accelerates the death of hair follicle cells.
- Autophagy is too low (Defective Autophagy) The accumulation of waste within cells leads to the destruction of essential proteins necessary for new hair growth. This results in insufficient energy supply to hair follicle cells. Additionally, waste that is not eliminated within the cells can cause inflammation at the hair follicles, leading to faster hair loss. The life cycle of hair strands becomes shorter, ultimately resulting in hair loss and thinning.
Causes of autophagy dysfunction include stress, deficiency in omega-3 fatty acids and polyphenols, aging, chemotherapy, and intracellular energy deficiency (low ATP).
What is Hairvivine-Pro™?
Hairvivine-Pro™ This is an extract from Styrian pumpkin seeds, rich in amino acids and polyamines, which stimulate the autophagy process. It contains components that aid in the production of ATP (adenosine triphosphate) in mitochondria, the organelles that function as the cell's energy factories. By converting food and oxygen into ATP, this very property has led to its adoption in the global market. Hairvivine-Pro™ It is an ingredient in numerous hair and fur care products, including those that reduce hair loss, increase hair thickness, and nourish eyebrows and eyelashes. Hairvivine-Pro™ which is an extract from Switzerland and Spain that AloEx has selected, is also an extract that has received the BSB Innovation Award Natural Products 2023 and the BSB Innovation Award Environment 2023.
How does Hairvivine-Pro™ help with hair loss?
Mainly, Hairvivine-Pro™ It helps the cellular waste removal system, or autophagy, function normally. When autophagy works properly, hair follicle cells become stronger, reducing inflammation, which is one of the causes of hair loss. It also increases ATP in mitochondria, the main energy source for all cells in the body, including hair follicle cells, which are essential for hair growth and division.
- When ATP levels are high, it helps prolong the growth phase (Anagen Phase) of hair follicles in the scalp. This is because ATP promotes the function of hair follicle cells and reduces inflammation.
- When ATP levels are low, hair enters the resting phase (Telogen Phase) more quickly because it weakens hair follicle cells and accelerates their deterioration.
Clinical Test Results of Hairvivine-Pro™
The clinical test results have been categorized Hairvivine-Pro™ There are two key components: clinical test results from volunteers who applied Hairvivine-Pro™ to the scalp area and clinical test results from volunteers who received Hairvivine-Pro™ Apply to the eyelashes.
Hairvivine-Pro™ At a concentration of 11 TP3T, it can help reduce hair loss by up to 181 TP3T.
Hairvivine-Pro™ At a concentration of 31 TP3T, it can help reduce hair loss by up to 32 TP3T.
Hairvivine-Pro™ At a concentration of 11 TP3T, it can increase hair density by up to 6.81 TP3T.
Hairvivine-Pro™ At a concentration of 31 TP3T, it can increase hair density by up to 14.51 TP3T.
On the 28th day, eyelashes grew four times longer compared to the results of the placebo.
Day 56: Eyelash length increased by 6.6 times compared to the placebo results.
On day 28, the diameter of the eyelashes increased (the lashes became 16 times thicker) compared to the results of the placebo.
Day 56: The diameter of the eyelashes increased (the lashes became 11 times thicker) compared to the results of the placebo.
Guidelines for selecting products containing Hairvivine-Pro™ as an ingredient
Selecting Products That Are Available Hairvivine-Pro™ To achieve results as recommended by clinical trials, it is essential to select a product that has Hairvivine-Pro™ It is a mixture at a concentration of 1 – 51 TP3T.
- Hairvivine-Pro™ At concentrations of 1–31 TP3T, it can help reduce hair loss and increase hair density on the scalp. The concentration of 31 TP3T is more effective in reducing hair loss and stimulating new hair growth than 11 TP3T.
- Hairvivine-Pro™ At a concentration of 5%, it can help enhance the strength and density of eyelashes.
